Clinical outcomes of gastric polyps and neoplasms in patients with familial adenomatous polyposis

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Clinical outcomes of gastric polyps and neoplasms in patients with familial adenomatous polyposis

Background and study aims Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome caused by a germline mutation in the adenomatous polyposis coli (APC) gene, characterized by the presence of more than 100 adenomatous polyps in the colorectum. The upper gastrointestinal tract is an extracolonic site for malignancy in patients with FAP. The frequency of death in Japanese patients w...

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Gastric and duodenal polyps in familial polyposis

Endoscopy with multiple biopsies of the upper gastrointestinal tract was repeated yearly over a two to six year period in nine patients with familial polyposis coli from three families. Adenomatous polyps, one to 20 in number and 2-8 mm in size, were detected in the antrum and the first and second duodenal portions in seven patients, while hyperplastic polyps were detected in four patients in t...

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Prevention and management of duodenal polyps in familial adenomatous polyposis.

Correspondence to: Mr L Brosens, Department of Pathology, Academic Medical Center, Meibergdreef 9, Amsterdam 1105 AZ, the Netherlands; l.a.brosens@ amc.uva.nl _________________________ F amilial adenomatous polyposis (FAP) is one of two well described forms of hereditary colorectal cancer. The primary cause of death from this syndrome is colorectal cancer which inevitably develops usually by th...

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A Preponderance of Polyps: Sequelae of Familial Adenomatous Polyposis

A man in his fourth decade with familial adenomatous polyposis (FAP) and previous colectomy due to colon adenocarcinoma underwent esophagogastroduodenoscopy (EGD) to investigate 3 days of nausea, epigastric abdominal pain, and coffee ground emesis; no source of bleeding was found. During the endoscopy, patchy mucosal abnormalities throughout the duodenum were identified and biopsied (Figure 1)....

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Evaluation of endoscopic characteristics of upper gastrointestinal polyps in patients with familial adenomatous polyposis.

BACKGROUND Familial adenomatous polyposis (FAP) is a disease inherited in an autosomal dominant fashion. Most FAP patients develop upper gastrointestinal polyps; especially those in the antrum and duodenum are usually neoplastic. The aim of this study was to evaluate the prevalence of gastroduodenal polyps in Iranian FAP patients. MATERIALS AND METHODS 28 patients affected by FAP underwent fr...

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ژورنال

عنوان ژورنال: Endoscopy International Open

سال: 2017

ISSN: 2364-3722,2196-9736

DOI: 10.1055/s-0042-119809